Human Stem Cell
Only the cell culture supernatant of healthy Japanese umbilical cord is sold as a product. Cultivation and manufacturing of the product are all performed in Japan, five strict tests are conducted in the manufacturing process, and only the cell culture supernatant that meets all the inspection standards is handled, so it is a product with extremely high safety.
The American Academy of
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Metabolic Medical Institute
Metabolic Medical Institute (MMI) was founded in 2014 as the branch of A4M that houses and contains all of the advanced medical education available to practitioners and allied health professionals.
Human Stem Cell
Human Stem Cell culture supernatant
We handle highly rare cell culture supernatants
that meet strict standards
A human stem cell culture supernatant with “world top level” quality produced by researchers who have been engaged in regenerative medicine and stem cell research in academia for many years.
High-precision multiple inspections are performed, and only cell culture supernatants that meet all inspection standards are used. We use an extremely small amount of media and reagents. Only this way a safe reliable product will be provide.
Cells collected only from Japanese donors culture and manufacturing only in Japan. We provide the highest quality supernatant under a thorough safety management system. Culture and manufacturing are all done in japan.
In order to maintain quality safety, only products that are stored at -70°C or less and are within 6 months of manufacture are carefully selected as undiluted products. We provide the highest quality and high concentration of cytokines and growth factors.
To ensure product safety, we carry out the following five
inspections in the manufacturing process and provide only
products that meet all standards.
1)Donor virus test
Blood tests are conducted twice
before and after tissue collection
We respect the window period of 92 days to collect the second blood sample from the donor, thus completely ruling out the possibility of tissue infection.
- All tests negative HBV HVC HIV HTLV PVB-19 syphilis
- The virus inspection items are based on the Ministry of Health, Labor and Welfare “Act on Ensuring Safety of Regenerative Medicine”.
- For the setting of the window period, refer to the Ministry of Health, Labor and Welfare “Estimated window period and retrospective period of infectious disease inspection”.
Inspection in Manufacturing Process
After confirming again that there is no viral or bacterial contamination, also ruling out
contamination by fungi and mycoplasma in the culture process, and that the endotoxins
are not above the standard value.
2) Virus Inspection
3) Mycoplasma negative
- All virus test are negative HBV HVC HIV HTLV PVB-19 CMV EB WNV
- Negative mycoplasma test
*The virus inspection items are based on the Ministry of Health, Labor and Welfare “Ensuring the quality and safety of human somatic stem cell processed drugs”.
4) Sterility test
5) Endotoxin test
■ Sterility test
Negative growth of various bacteria(fungi)
Confirm no bacterial growth
■ Endotoxin test
Confirmed that the endotoxin concentration in the
culture supernatant is less than 0.5 EU/ ml
Various TROPHIC effects have been confirmed
Cell culture supernatant is rich in hundreds of cytokines. Cytokines have the function of promoting cell growth and repair.
The interaction of cytokines with different properties creates a synergistic effect and leads to cell activation.
Retaining the original “Golden Ratio” of Humans
Based on the concept of cytokine orchestra, we willdeliver the undiluted supernatant liquid without adding any specific cytokine to the cell culture supernatant that we provide.
DOMESTIC MARKET TRENDS
Currently, there is almost no circulation of cell culture supernatant derived from Japanese donors and Japanese-made umbilical cords. We provide the cell
culture supernatant derived from Japanese umbilical cord, which is extremely rare in the market.
Mainly derived from Fat
Due to the ease of tissue collection, the main source is a Japanese donor and adipose-derived fat.
Derived from Dental Pulp ≒Derived from the milk tooth pulp
Due to the spread of deciduous tooth banks, pulp derived from pulp tooth is the mainstream, and it is the second most distributed after fat.
Cord Blood is from overseas
Umbilical cord blood derived culture supernatants are mainly produced overseas such as Korean and American products.
A4M JAPAN MMI
A4M American Academy of Anti-Aging Medicine Japan
We provide the latest practical medical information on anti-aging・ prevent medicine, which has received the most attention in the world including the United States.
A4M JAPAN International Conference Scheduled
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MMI Medical Education Program
MMI Offers educational programs for medical professionals based on the world`s latest medical information
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|Date of Establishment||29, Jan 2020|
|Main Business||Global Doctor Networking|
|Correspondent Banks||Mizuho Banking Corporation Kudan Brunch|